Browse-BactMentha

Display specific BactMentha datasets

BactMentha dataset filtered on host taxa:

Click on a taxon button to display the BactMentha database pathogen-host protein-protein interactions for the corresponding host taxon.
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All Data

Human

Mouse

Rat

BactMentha dataset filtered on pathogen categories:

The World Health Organization (WHO) Priority Pathogens are infectious microorganisms considered a significant threat to global public health, often due to their potential for causing severe outbreaks or limited treatment options. According to the European Union classification system of biological agents, hazard groups (from 1 to 4) categorize, based on their risk, those which may affect the human health (https://www.hse.gov.uk/pubns/misc208.pdf). Click on the following buttons to filter the BactMentha Datasets and display only the interactions involving pathogens in either WHO priority list or in an Hazard group. (Filter on Hazard groups 1 and 4 have not been added as no such pathogens are found in BactMentha).

Who priority
or
Hazard groups

Who priority

Hazard group 2

Hazard group 3

BactMentha dataset filtered on Human-Bacteria annotated protein interactions:

Experimental data have been recovered on some protein-protein interactions, which permit to get more details on the binding regions on either host protein side, pathogen protein side or both. The Ontology Search (OS) definition of those binding regions can be found here. Moreover, mimicINT tool have been used to infer some interaction interfaces between Human proteins and bacterial proteins based on known domain-domain or domain-motif templates of interaction. Click on the following buttons to display only the Human-Bacteria protein-protein interactions for which there are known experimental binding regions (BR) on at least one protein side or mimicINT predicted interfaces (MI) of interaction (always both sides).

Binding regions

mimicINT interfaces

Bacterial pathogens in hazard group 3

Taxon ID	Taxon Name	Taxon Family	Hazard Group	WHO priority	Interactions
1392	Bacillus anthracis	Bacillaceae	3	NULL	3006
585396	Escherichia coli O111:H- (strain 11128 / EHEC)	Enterobacteriaceae	3	critical	1
155864	Escherichia coli O157:H7 str. EDL933	Enterobacteriaceae	3	critical	0
334380	Orientia tsutsugamushi (strain Ikeda)	Rickettsiaceae	3	NULL	9
632	Yersinia pestis	Yersiniaceae	3	high	4137
83332	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Mycobacteriaceae	3	critical	188
452659	Rickettsia rickettsii (strain Iowa)	Rickettsiaceae	3	NULL	5
119856	Francisella tularensis subsp. tularensis	Francisellaceae	3	NULL	23
177416	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	Francisellaceae	3	NULL	1652
83334	Escherichia coli O157:H7	Enterobacteriaceae	3	critical	171
224914	Brucella melitensis biotype 1 (strain ATCC 23456 / CCUG 17765 / NCTC 10094 / 16M)	Brucellaceae	3	NULL	4
652616	Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)	Mycobacteriaceae	3	critical	187
90370	Salmonella typhi	Enterobacteriaceae	3	high	4
227377	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	Coxiellaceae	3	NULL	424

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